The Effectiveness of Compression Therapy in the Prevention of Venous Thromboembolic Complications in Patients With COVID-19

Background The main method for preventing thrombotic complications in patients with coronavirus infection is anticoagulant therapy (ACT). However, its use not always possible, particular bleeding. only of prevention this case elastic compression (EC) the lower extremities. Aim study To evaluate effectiveness extremity EC venous thromboembolic (VTEC) a new infection. Material and methods was approved by local Ethics Committee Ryazan State Medical University Ministry Health Russian Federation registered on ClinicalTrials.gov platform (identifier NCT05143567). included 69 without prophylactic (Group 1) 65 who used stockings 2). were treated covid hospital from July to November 2021. All had verified infection, they took ACT underwent ultrasound duplex scanning veins extremities upon admission, intensive care unit discharge. We assessed frequency (VTEC), hemorrhagic complications, mortality. assess severity bleeding, classification International Society Thrombosis Haemostasis (ISTH) used. Results In there 7 VTEC cases (10.14%); deep vein thrombosis (DVT) — 4 (5.8%), pulmonary embolism (PE) 3 (4.3%). 6 (8.7%) PE fatal. It noted that 2 (2.8%) autopsy, clinically. 2nd group compression, overall incidence one (1.6%). When analyzing bleeding 1st group, (1.4%), also intense intermuscular hematoma Significant observed patient (1.4%) (4.8%) group. minor 11 (15.9%) 8 (12.7%) mortality during hospitalization (without EC) (11.1%) (with (p=0.419). Conclusions higher than Patients wearing low (1.6% versus 10.14% 1, p=0.039). groups same (group 1 preventive at inpatient stage treatment makes it possible prevent when possible.